Abstract: Reviews were made on selection of plantation location, seedling management, pruning, flower and fruit management, water, soil and fertilization management and pest control of Citrus×aurantium ‘Changshanhuyou’. Presentation was made on parental source of C.×aurantium ‘Changshanhuyou’ and its habitat for cultivation. Qu Aurantii Fructus is dried immature fruit of C.×aurantium ‘Changshanhuyou’, with flavonoids, volatile oils and other chemical substances. Among them, flavonoids are the main pharmacodynamic material basis of Qu Aurantii Fructus. Research showed that Qu Aurantii Fructus had functions of antioxidant, hypolipidemic, antibiosis, antidiabetics, etc. The possible influence of C.×aurantium ‘Changshanhuyou’ cultivation technology on the effect of Qu Aurantii Fructus was analyzed. Research aims to further exploit Qu Aurantii Fructus to stimulate the cultivation industry of C.×aurantium ‘Changshanhuyou’, and promotes the modernization of traditional Chinese medicine and the standardization of the quality of traditional Chinese medicine.