Abstract: Experiments were conducted on inhibiting effect of solution with different concentration of extracts from episperm of Ginkgo biloba against 8 common mould strains on culture media, and determination was made on preservative effect of Liquidambar formosana wood. The result showed that solution with 0.5g/L extracts had inhibition effect against tested strains, and similar effect of H₃BO₄ against Aspergillus versicolor, Postia placenta, A. niger, A flavus and Trametes versicolor, and even better effect against Lasiodiplodia theobromae compared with H₃BO₄. Solution with 1g/L and 2g/L extracts had same effect of H₃BO₄ against Trichoderma viride and Penicillium visidicatum. L. formosana wood treated by cold maceration in solution with 1g/L extracts with retention of 0.23 g/m².of wood got mildew-proof grade I.